Interleukin-1 Receptor 2 Keeps the Lid on Interleukin-1α
نویسندگان
چکیده
منابع مشابه
The interleukin-2 receptor.
The human body defends itself against foreign invaders such as bacteria and viruses by a defense system that involves antibodies and thymus-derived lymphocytes (T cells). A major advance over the past decade has been the demonstration that the diverse cells within the immunological network communicate with each other not only by cell/cell contact but also by an array of hormone-like proteins te...
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The IL-2 toxin-mediated inhibition of protein synthesis in high affinity IL-2-R-positive murine and human T cell lines has been examined. Both excess free IL-2 and mAb to the Tac epitope of the p55 subunit of IL-2-R are shown to block the action of IL-2 toxin; whereas, agents that interact with other receptors or antigens on the T cell surface have no effect. We show that IL-2 toxin, like dipht...
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ژورنال
عنوان ژورنال: Immunity
سال: 2013
ISSN: 1074-7613
DOI: 10.1016/j.immuni.2013.02.001